Analysis of Two Major Intracellular Phospholipase A2s in Mast Cells Reveals Crucial Contribution of cPLA2α, not iPLA2β, to Lipid Mobilization in Proximal Mast Cells and Distal Fibroblasts

From the Lipid Metabolism Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 256-8506, Japan; Department of Health Chemistry, School of Pharmaceutical Sciences, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan; Department of Biochemistry and Molecular Biology, Department of Lipidomics, and Department of Metabolome, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; The Laboratory of Molecular Genetics, Department of Medical Genetics, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan; and Core Research for Evolutional Science and Technology (CREST) and Precursory Research for Embryonic Science and Technology (PRESTO) of the Japan Science and Technology Agency,, 4-1-8 Honcho Kawaguchi, Saitama 332-0012, Japan; Institute for Advanced Biosciences, Keio University, 246-2 Mizukami, Kakuganji, Tsuruoka, Yamagata, 997-0052, Japan; College of Life and Health Sciences, Chubu University, 1200 Matsumoto-cho, Kasugai, Aichi 487-8501, Japan.